![]() ![]() ![]() While the international version still received critical acclaim for its gameplay and graphics, the decision to remove most of the plot was heavily criticized by Western critics and gamers, since Namco initially advertised that the Western release would featured all the content seen in Japanese version. To accommodate for the Japanese plot not being translated, all story related voice acting and cut-scenes were removed, along with the plot being rewritten to a more basic story with no voice acting. While Namco never officially explained why this occurred, many speculated it was due to sales being lower than expected for the Japanese release, along with the impending release of the PlayStation 2. Download PEPSI Man ROM to your computer and play it with a compatible emulator. English voice acting was planned and started recording in the early stages, but Namco cut the funding for the translation efforts. PEPSI Man ROM download is available below and exclusive to. While nothing was changed from the overall gameplay, its campaign was stripped down to a 1-disc 36 mission campaign with no branching paths. It also featured fully voiced anime cut-scenes, along with in-game radio chatter.The international version of Ace Combat 3 was released in 2000. CD-ROM Software Library Software Sites Tucows Software Library Shareware CD-ROMs. Ini sangat seru untuk di mainkan bersama saudara atau teman teman anda. Siapa sih yang ga tau game ini Tentunya anda sudah tau game ini. The Japanese version of Ace Combat 3 released in 1999 featured a lengthy 2-disc campaign of 52 missions that were split among different paths depending on in-mission decisions, along with multiple endings and multiple factions for the player to join. PepsiMan PS1 ISO Free Download Games for PC Gratis dan Instal dengan mudah game ini. The third installment in the Ace Combat series of console flight simulation games, Electrosphere takes the contemporary setting of the first two games into a story set in the mid-21st century, involving a war between multinational corporations.The game is notable for having two radically different releases for the Japanese and Western markets. Along with clever moves to avoid obstacles, players also have to try to collect Pepsi cans for a limited time to improve their scores.Ace Combat 3: Electrosphere (エースコンバット3 エレクトロスフィア, Ēsu Conbatto San Erekutorosufia) is a flight simulation game made by Namco for the PlayStation game console. Note, continuous collision with obstacles will cause the player to be deducted a life and must play again. It was released in Japan on March 4, 1999, and is based on the American carbonated soft drink Pepsis eponymous superhero mascot. Therefore, people need to watch quickly to avoid colliding with them. When you click on the link to Github the first link you land on will be the Home tab, this tab explains how to use the Megathread. Besides, the game possesses its type of obstacles, and they will constantly appear along the way. ![]() Players can move to the left, right, jump into the air, or crouch. EDIT Okay, its possible I have a working ROM, Im not sure, but now Im looking for Japanese BIOS. The scenes that appear in the game include three views made based on real-life (Texas, San Francisco, and New York City) and a fictional setting (Pepsi City).Īt the stages of the game, the character will automatically move, and the player is tasked with customizing various control manipulations to overcome obstacles. The game is built in four stages, and each step will bring its context for people to perform the tas. Pepsiman (Japan) ISO download is available below and exclusive to CoolROM. Players will control the character through a third perspective and have the task of overcoming many obstacles present along the way to collect Pepsi cans. Download Pepsiman (Japan) ISO to your computer and play it with a compatible. ![]() The camera changes to a man holding some snacks and 5 pepsi cans is seen walking out of the store.'Hey,lets start the game'he says. Story: A hand is seen opening a refrigerator and it took 5 pepsi cans. Pepsiman’s challenges are relatively easy to understand. The most complete collection of all things Pepsi-related in retro gaming. Pepsiman is a 3d action game that takes place over four stages splits in three sections. ![]()
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![]() ![]() ![]() ![]() The work on the end wall took place in an environment of heightened radiation and we are very proud that it was finished without any accidents or negative impact on the workforce. Vince Novak, EBRD's nuclear safety director, said: "Strong progress has been made in difficult circumstances. Extensive testing is already under way before the structure will be commissioned and handed over to the management of the Chernobyl Nuclear Power Plant (ChNPP)." The European Bank for Reconstruction and Development (EBRD), which is managing funds for the project, said today: "Installation of critical cranage, ventilation and control systems is nearing completion and the final stages of sealing the confinement of the old structure is under way. The process of sliding the arched structure from its assembly point into position over unit 4 was completed on 29 November 2016. The NSC is designed to withstand temperatures ranging from -43☌ to +45☌, a class-three tornado, and an earthquake with a magnitude of 6 on the Richter scale. It will make the accident site safe and with a lifetime of 100 years will allow for the eventual dismantling of the ageing makeshift shelter from 1986 and the management of the radioactive waste. The NSC is the largest moveable land-based structure ever built, with a span of 257m, a length of 162m, a height of 108m and a total weight of 36,000 tonnes equipped. The enormous arched structure was put in place one year ago and is expected to be commissioned in the first half of 2018. Installation of critical systems is progressing within the New Safe Confinement (NSC) covering the damaged unit 4 of the Chernobyl nuclear power plant in Ukraine. ![]() ![]() TiddlyDrive Add-on for Google Drive by Joshua Stubbs.Signing the Contributor License Agreement.PESpot Lesson Planner by Patrick Detzner.Interactive Git Documentation by Devin Weaver.datepicker plugin based on Pikaday, by kixam."X3DOM for TiddlyWiki 5" by Jamal Wills."Un wiki sur votre BiblioBox avec TiddlyWiki" from A Penguin in Redmond. ![]() "TW5 Tribal Knowledge" from Scott Kingery."TiddlyWiki5^2 documenting while learning TiddlyWiki5" by Iannis Zannos."TiddlyWiki Knowledge Network" by Dmitry Sokolov."TiddlyWiki guide FR" by Sylvain Naudin."TiddlyWiki for Scholars" by Alberto Molina."Tekan: Kanban that stays with you" by Riz."TB5 - a pocket full of tips" by Tobias Beer."Setting Up a Personal TiddlyWiki Server on OS X" by Kris Johnson. ![]() "savetiddlers" Extension for Chrome and Firefox by buggyj."PETTIL - Forth for the Commodore PET" by Charlie Hitselberger."Notizen mit TiddlyWiki systemübergreifend nutzen" by Michael Sonntag."Moments: A little color won't hurt" by Riz."Install and run TiddlyWiki on a CentOS 6 VPS using Nginx" from RoseHosting."How Does Twederation Work" by Jed Carty."Hosting TiddlyWiki5 on GoogleDrive" by Tony Ching."Ghostwriter theme by Rory Gibson" adapted for TW5 by Riz."file-backups" Extension for Firefox by pmario."Encrypt single tiddler plugin" by Danielo Rodriguez."Creating a baby journal with TiddlyWiki 5" from A Penguin in Redmond. ![]() ![]() ![]() Pulse Width - the signal's duty cycle or time intervalĪrray - the repetition characteristics of the signal. LAUNCH O2-1 Scopebox User Manual 1 1 Introduction 1.1 Product Introduction The Scopebox is an optional add-on module, including automotive oscilloscope and automotive ignition waveform. The scopebox can record and display electrical signals and their waveforms, as well as compare and examine them according to pre-determined parameters. This helps you save time when running a vehicle diagnostic, and also reduces the costly expenditure spent on unnecessary replacement parts. LAUNCH O2-2 ScopeBox For Solving Complex Electrical Faults LAUNCH O2-2 ScopeBox For Solving Complex Electrical Faults 0 reviews 750.00 Looking for help or Get More Discount Please contact WhatsApp: +1 9 Brand: Launch X-431 Product Code: LPD113-B Availability: In Stock Weight: 5.20kg Size (LxWxH): 17cm x 5.40cm x 14. Meantime, this intelligent diagnostic tool can show 12 waveform graphs on 1 screen or combine 4 items in a graph to intuitively compare data. These signals can then be analysed by the Scopebox, which may reveal whether or not there are actually any faults with the sensors, actuators, circuits or electronic control units. 2.One key enable function allows users to capture a particular waveform which makes the process 70% more efficient as compared to other scopes.ģ.Access to 23 variants of automatic measurements that are displayed on one screen for an easy switch.Ĥ.Ability to input names and characters directly by clicking on the virtual keyboard, this operation streamlines the process and contributes to 90% efficiency.ĥ.Use the zoom in/out feature to review precise details.Ħ.Customizable personal system settings that can be saved as configuration files for viewing.ħ.The self-calibration function allows optimization of the oscilloscope signal path for maximum measurement accuracy.Ĩ.Magnifies waveform math operations, such as addition, subtraction, multiplication and FFT function for high level waveform analysis.ĩ.Multiple automotive tests include circuits, sensors, actuators, ignition tests and more.The Launch Scopebox allows you to transform your Launch X431 GDS or X431 Europad 2 into a 4 channel Lab Scope, which can quickly identify, locate and isolate suspect & intermittent signals. ![]() 1.Features the ability to record and playback high-resolution waveform data for future analysis.There are some things to know before you use a price comparison app: Make. Featuring a new design and upgraded hardware, the LAUNCH O2-1 Scope Box is a. Video scope software, for the most part, requires its own computer and hardware to run, but ScopeBox 3.3 breaks that tradition with a new feature called ScopeLink. Warranty & Support valid for Genuine Purchase in Singapore by LAUNCH SG. Extensive library of known good waveforms Waveform auto-setup on all 4 channels. LAUNCH O2-1 Scope Box Compatible with the X-431 PAD VII, X-431 PAD V, X-431 PAD III V2.0 LAUNCH O2-1 Scope Box Compatible with the X-431 PAD VII, X-431 PAD V, X-431 PAD III V2.0 0 reviews 750. By integrating with the X-431 series scan tools via O2-2 application, it delivers accurate and conclusive diagnostic faults that enable the shop and technician to enlarge their scan tool’s functionality. The apps are also useful if youre just bargain hunting, as many of them show you the latest deals and flyers from stores. Enter a product like ScopeBox which is 100 stand-alone video scope software. LAU301020519 - Launch GDS Scopebox Module. LAUNCH X431 O2-2 Scopebox analyze data Solving Complex Electrical Faults for launch PAD V /PAD VIIįeaturing a new design and upgraded hardware, the LAUNCH O2-2 Scopebox is a versatile and easy to use add-on module that can detects high level faults on various electrical components, such as sensors, acturators and circuits. LAUNCH O2-2 Scopebox is a versatile and easy to use add-on module that can detects high level faults on various electrical components, such as sensors. ROG Strix Scope TKL, alma ortamnzda ok daha geni fare hareketleri yapabilmeniz iin alan yaratan, kk boyuta sahip, yksek performansl mekanik. ![]() ![]() ![]() ![]() The LaMarche Model A36D Controlled Ferroresonant Rectifier/Power Supply has many inherent advantages such as voltage regulation, high efficiency, high power factor and short circuit protection. The system’s controller supports today’s advanced remote monitoring capabilities, such as web server and SNMP protocol via Ethernet RS232 and RS485 ports. With its 3 tier configuration, the system supports up to 72 breakers total Rectifier output, DC distribution and batteries are all connected to an internal common 2300A bus. Each tier is designed for load shedding with a 600A in-line LVLD contactor, which is followed by 24 breaker positions. Enclosed in a 7’H x 26”W x 26:D box frame, the system has 3 tiers of front accessible plug-in break distribution panels. This modular 1800 amp -48vdc (positive ground) power system is the ideal choice for communication centers, data centers and microwave applications. It combines the load distribution breakers, LVLD, interface, ground/charge bars and High Frequency modular rectifiers into a 23” rack mount unit. The LMPS is equipped with a user friendly system controller, DC distribution and provisions for future expansion. The La Marche LMPS is specifically designed as an all in one solution that integrates our High Frequency rectifiers with our distribution center. Its AC input line regulation operates over a range of 185-264 volts, with a frequency range of 45-66Hz.ge can hold up to 4(four) 20 Amp rectifiers which will provide a total of 80 Amps of power. Adverse power conditions do not affect the A96 DC output. Complete front panel accessibility and a plug-and-go design ensure quick, convenient installation without the possibility of wiring errors. The loss of one rectifier will not affect the operation of the remaining rectifiers. The A96 is more than a rectifier/battery charger, it is also a power supply/battery eliminator. With current limiting circuitry, voltage regulation, high efficiency and high power factor, the A96 is the ultimate modular rectifier for Utility applications. There is no need to shut down the system to change a rectifier. The LaMarche A96 provides highly reliable, hot swappable 130 VDC power with full load sharing capability in a compact, modular rectifier system.Īt a height of only 4RU in a four across 23″ rack configuration it offers high power density combined with high efficiency. Seethe Case Specifications chart on the other side of this DataSheet for further details. ![]() Some units can be wall, floor or rack mounted and others can be wall or floor mounted. The unit is convection cooled and the components are designed to achieve MTBF in excess of 100,000 hours. The battery chargers are designed for dependable operation in harsh environments at temperatures up to 122oF (50oC). The A75D/A75DE series is offered with DC output voltages of 24,48 or 130 VDC with DC output currents from 6 to 100 Amps.These chargers can be powered with 120, 208, 240 or 480 VAC.The current limit is factory set at 110% and is adjustable from 50to 115%. The A75D/A75DE battery charger is a solid state unit utilizingSCR technology and has ☐.5% regulation from no load to full load over the specified input voltage, frequency and ambient temperature range. Compatible with all types of vehicles - Charge and maintain cars, motorcycles, lawnmowers, ATVs, tractors, trucks, SUVs, boats, classic cars, hot rods, and more - you name it.The La Marche Model A75D/A75DE Series Battery Chargers are engineered for the demanding requirements of Switchgear, Process Control and Oil Exploration to name a few.Restore your battery - Detects sulfation and acid stratification and restores lost performance for stronger engine starts and extended battery life.A fully-automatic, worry-free battery charger for year-round use. Simple to set up and use - Plug-in, connect to the battery, select a charge mode, and start charging your battery.Or use the all-new Force Mode that allows you to take control and manually begin charging dead batteries down to zero volts. Charge dead batteries - Charges dead batteries as low as 1-volt.Enjoy precision charging - An integrated thermal sensor detects the ambient temperature and alters the charge to eliminate over-charging in hot climates and under-charging in cold climates.Do more with Genius - Designed for 6-volt and 12-volt lead-acid automotive, marine, and deep-cycle batteries, including flooded, gel, AGM, and maintenance-free, plus lithium-ion batteries.And it's simpler and easier to use than ever before. It's 34% smaller and delivers 65% more power. Meet the GENIUS5 - Similar to our G3500, just better. ![]() ![]() ![]() Hyper Light Drifter is planned for PC (Linux, Mac OS and Windows) PlayStation 4, PS Vita, Ouya and Wii U, and a release by the end of the year, or early 2015. "There's plenty of good pixel art out there, but there are specific things that I like, which is color, and blending, and light. "So I decided to go with a much lower resolution, pixel-art basically, as long as I could make it my own," he said. Preston said originally the game was going to be " a full HD, very illustrated concept," but in early prototypes he realized that it would be too much work for one person. Hyper Light Drifter sought just $27,000 when Heart Machine took this concept to the crowd it raised nearly $650,000 from almost 25,000 backers, its appeals to old school gaming resonating deeply, as well as its soothing soundtrack and pixelated visual style. What really makes it for me are the environments and the sense of exploration." The creatures in the world also are a part of that. "Really it's about the designs of the world, and being able to roam in this world that I've had a desire to create for a long long time. "I had a lot of ideas for a world I wanted to create," Preston said, when I asked what creative itch this game was meant to scratch. They'll have to come to their understanding of it on their own. Hyper Light Drifter may be an allegory for Preston's personal story but it's not one he's going to impose on players, to force them to empathize with the rather serious challenges he has faced. The soft-spoken Preston mentioned none of that to me, though he doesn't hide it, and has discussed it in other interviews. It's directly analagous to the heart condition Preston has battled since birth (and, of course, the studio's namesake.) ![]() The Drifter is on a mission to a ruined, violent world, hoping to find some means of curing or at least quieting the mysterious disease that haunts him. "I think people are very curious about the story, but I always say the same thing, which is, 'You'll get to it when you play it.'"Įven if they're showing off the singleplayer campaign now (it will feature drop-in/drop-out co-operative gameplay), it's clear they want this to be as personal an experience for the player as it is for them, Preston in particular. Movie trailers blow it all the time, and some games are like 'We're doing this, and we're doing that,' and you get into the story before you even play the game." I don't want to talk about, because it's important. "I think people are very curious about the story, but I always say the same thing, which is, 'You'll get to it when you play it,' because for me, that's such an integral part of the experience," Preston said. In past exhibitions, he and Teddy Diefenbach, the co-founders of Heart Machine, had only been showing a co-operative arena mode. "I'm not talking too much about the story, just because it's something I'd like people to experience on their own," Preston told me after I played one stage of the game's main campaign. I'll add stuff as people post or I hear more.Alex Preston still is keeping mum on what the story is with Hyper Light Drifter, the stylized action role-playing game that became an indie game to watch for this year after it obliterated a modest five-figure Kickstarter goal back in October. West: Midnight Wood / Crystalfire Brink (combines to Crystalfire Wood) Judgement / The Perfect Immortal Cell (Abyss) Gun from South? (I haven't got this one yet)Įnemies: (Boss names are from the tarot cards) Heavy Pistol (West, our joke name so far is "The Hummer")īeta Shotgun (East, 8 Module door, from the demo) Money: Gearbits which make Gearbytes (Upgrade Bits?) Is there a list of what things are called some where? Here's what I've heard so far: I like how minimalist the game's interface is, but it makes it hard to talk about the 'things' you find. ![]() ![]() ![]() The most interesting feature is that you will invite your friends to play the game. Moreover, the game has also come with an ads-free feature, which helps me focus only on the game. Moreover, it is easy to unlock the characters (with DLS 2022 MOD APK) and provides unlimited diamonds, which is truly important. This game comes with several graphics background, which provides realistic feelings. I still play the game with great fun and enjoyment. ![]() Dream League Soccer 2022 MOD APK Reviews: You just need to use Mod Apk and get all of the things free and ads-free performance. Yes, you are hearing the right information. The unlimited coins, money, and pro features are free when you are using MOD APK. Play the game with realistic graphics without paying any money for the features. How to Get Unlimited Money & Pro Features from DLS 2022 MOD APK? You can invite your friends to play the game.The game provides you high dame without paying any money.It comes with unlimited money and unlimited gems as well as unlimited coins.So, before downloading the game, you should check out the following points. These features are ready to clear your confusion about the game and help you to understand whether the game is suitable for you or not. Are you still thirsting for more information? If yes, you can check out the following sections. There are couples of players and backgrounds you will discover from this game.īut what about unlimited gems, unlimited money, unlimited diamond, and unlocking the characters? Well, you will get all these features free when installing DLS 2022 MOD APK. You will play the game with your family and friends because the invitation functions. This Dream League Soccer 2022 game is truly a fun and adventure game online. It has a fun gameplay, good graphics, and a ton of well-known teams and players.New Updated Features of DLS 2022 MOD APK How to Get Unlimited Money & Pro Features from DLS 2022 MOD APK? Dream League Soccer 2022 MOD APK Reviews: Some Users Review This DLS 2022 MOD APK FAQs (Frequently Ask Questions) Q: How can I download DLS 2022 game on my PC? Q: Is this game free or paid? Q: Is this game suitable for IOS? Conclusionsįootball is a popular game both online and offline. ![]() Basically, with these three buttons, you can play soccer.ĭream League Soccer is an amazing soccer game for Android. With these options, you can make walls, pass deep, dribble down the field, lob the ball towards the goal, fire the ball across the field, etc. You'll have only three buttons: pass, shoot, and center, which will be more than enough to enjoy the amazing gameplay. All of this will influence your matches.īut the real fun starts once you enter the game simulator. After you're done, you can start playing in a league against various mediocre teams that you'll have to beat to start claiming more and more victories.ĭuring your adventure, you can also manage various aspects of your team: improve the stadium, try new strategies, make signs, and check the stats for your starting lineup. When you start the game, you'll need to choose a team name, design your equipment, and choose a captain. Dream League Soccer is a soccer game where you lead your team to victory, starting from humble beginnings at the bottom of a fictional league in which various teams from all over Europe are competing. ![]() ![]() The first, Elsa Eliane is a new recruit for the EC Armored Tactics Research Corps, the "Durnadal". One scenario takes place in the European Commonwealth (EC) and the other scenario takes place in the United Continental States (UCS). FM4 takes place in two Scenarios simultaneously. The EP is spent on Skills, or upgrading previous skills to a higher level. ![]() Characters also gain Enhancement Points (EP) Which are gained by destroying units and beating missions. Characters are restricted to only one Wanzer Each. Stronger parts and weapons must always be bought, with more coming in the further the player progresses - although some can always be acquired through battle simulations. Other changes to note: The Ability to strengthen a Wanzer's Qualities (Implemented from FM3) has been removed. Though players should take care when utilizing such a strategy as when a Link Battle commences that Persons AP also depletes, so if the Link system is spammed come the time when it's that characters move, they will have nothing to do. Using this function requires Link Points which the player assigns to each character. They can set them to Offensive or Defensive attacks and they will move accordingly. ![]() The Biggest Change is the Link system, a tactic players can use to have characters in their unit help each other.Radio backpacks have communications equipment that allows transport to drop supplies, armor coating, or call in an airstrike (which the player must wait two turns for). Jetpacks have built-in boosters that allow a Wanzer to scale buildings and directly bypass obstacles. Repair backpacks fix Damaged parts, and Status Effects. EMP backpacks hit a Wanzer with an Electromagnetic pulse and disable them for a set amount of time. Sensor backpacks are equipped with sonar and radar sensors that extend the firing range of missile launchers. New backpack types have been implemented into the battle system.With the exception of Melee and support Fire which can only be used once per battle. Players can now attack more than once, though only if the unit has enough Action Points (AP) to do so.Battles now operate with up to six units, though the player can access additional forces in certain missions. ![]() ![]() There's also been changes to the Battle system setting it apart from previous entries: Players should take that into account if they have certain equipment on a certain body part that can be useful in protecting the body. So even if the head, Arms and legs are at 0 Hit points, they can be fully healed. Destroying the arms prevents use of the weapon that is attached to that arm, Destroying the legs limits movement to one space at a time, Destroying the Body destroys the Wanzer completely. There are five points of damage that a Wanzer can take Head, Body, Left arm, Right arm and Legs. Moves are turn-based, with each member having a set amount of spaces to move and an array of weapons with a certain amount of range. Battles take place on a grid map with Members of each squad Piloting Mechs known as Wanzers. Much like the previous games, players progress through the game in a series of missions, which are driven by the game's overall narrative. In the game, players take control of two protagonists: Darril, a care-free and kind army deserter, and Elsa, a serious pilot in the small organization - the "Durandal." The two characters start off in their own stories, but further down the road the stories end up being inexorably intertwined. Front Mission 4 is a single player, tactical role-playing game, made by Square Enix. ![]() ![]() ![]() The contrast dye makes pathological processes stand out in organs and tissues that would otherwise be invisible or unclear. Not all pathology causes symptoms (e.g., many cancers cause no symptoms early on, but can be diagnosed with imaging). For MRI contrast, that purpose is to aid physicians, such as radiologists, in identifying pathology – abnormal processes that occur in the human body that can cause symptoms in a patient. What is the Purpose of Contrast in a MRI Scan?Įverything we do in medicine has an underlying purpose. ![]() Until that data exists, it will be treated conservatively and only given in patients with adequate kidney function (eGFR >30 mL/min/1.73 m 2 ). This agent is one of the newer agents and there currently isn’t enough data to determine the safety at this time. gadoxetic acid disodium salt (Eovist®, Primovist® ).They have been associated with minimal, if any, cases of NSF and are considered to be safe, even in patients with chronic kidney disease. These are the safest agents and the ones currently used in practice today. These are the contrast agents that led to concerns of nephrogenic systemic fibrosis (NSF), which we’ll cover below. Because of this, they are no longer used as intravenous (IV) agents. These are the earliest MRI contrast agents and the least safe. Gadolinium-based agents are split into three different groups. The macrocyclic agents generally hold on to the gadolinium more tightly than the linear agents. Some are “linear” with the gadolinium ion next to it (like a sunset with the sun sitting on top of the water ) and others are “macrocyclic” with a circular/spherical chelator surrounding the gadolinium ion (the chelator tightly “hugs” the gadolinium). The gadolinium ion is “held” onto by something called a “chelator.” Each different cegfrontrast agent has a different chelator, which is what differentiates contrast agents from one another. These types of contrast material are administered by injection through a peripheral IV (or occasionally into a joint) and imaging is performed prior to and after the injection of the contrast. Gadolinium agents actually contain only a very small amount of gadolinium and exist as clear liquids. Unsure if you really need an MRI scan or if a CT would suffice? Check out my article CT Scan vs MRI: What’s the Difference? to find out.‘Our’ refers to radiologists – the physicians who interpret the MRI exams.Gadolinium is a unique element that has ideal properties for MRI, which greatly improves our ability to see abnormalities on MRI scans. This is why MRI contrast is often referred to as “gadolinium based contrast agents.” Gadolinium, a rare earth metal naturally occurring on Earth, is the element that adds contrast to MRI images and is actually used in ionic form (meaning it’s missing a few electrons and has a positive charge). Intravenous MRI contrast agents do exactly what their name implies: they add contrast (our ability to tell two adjacent things apart from one another such as a tumor in the liver from normal liver tissue – see example below) to MRI images. The better question? SHOULD you refuse contrast agents? In this article, I’ll cover everything you need to know about MRI contrast material. If you’re asking yourself this question, “Can I refuse contrast dye for MRI scans?,” you no longer need to wonder! ![]() ![]() ![]() ![]() ![]() By comparing the myriad changes, we can fill in gaps to help treat those of different ancestry who are prone to certain conditions. This burgeoning genetic library will represent genomes across Homo sapiens so that we may better understand genetic variation among ourselves. Darryl Leja, NHGRI What is the pangenome? The new pangenome reference is a collection of different genomes from which to compare an individual genome sequence. Their work offers a starting point for comparing genetic variation so that we may better understand how genes vary and mutate across our species. Published today in the journal Nature, with authors from Canada, Denmark, Germany, Italy, Japan, Spain, the UAE, the UK, and the US, researchers created what they are calling the human pangenome reference consortium, a collection of sequenced human genomes that aims to eventually represent as many possible DNA sequences found across our species. Now, swaths of researchers around the world have been working to dive into that remaining, highly variable part of human DNA. Two decades later, scientists are still trying to unpack how that 0.4 percent influences us. That tiny fraction is also likely responsible for many diseases and conditions. Among the many things they discovered was that while any two humans have 99.6 percent of their genome in common, the remaining 0.4 percent leaves plenty of room for variation. Twenty years ago last month, scientists sequenced the first human genome in the landmark Human Genome Project. ![]() |